I'm not sure what setting it should go. Hell, I'm not sure why people want to go to Africa really. The technological gap is really small and I do like RTS games where sides are distinguishable enough via technological gaps for example. Sure I hate Heavy Tank Spam in CoH2 but it is possible to still win and I do think it makes fighting as the 'underdog' (Allies) more worth it when you win. I'm not sure how the map design for Africa would work too. I mean, most of the Relic games have a lot of cover around while the desert... not really. And yes, I played the Europe at War mod and the African settings, not a big fan of the desert map designs. If they moved away from the squad based tactics and more into the bigger picture thus there'd be less microing into cover and etc., then sure, the African setting could work if the game became a bit more macro.
I feel like most people want to go to the African setting not just understandably they want a new change of scenery, but I think there is this fascination people have with the Afrika Korps and Rommel