Yes. KV-2 is much much better at AI than IS-2 but is also less agile. Furthermore, it's penetration values are quite low so on the off chance it penetrates... sure. You do 240 dmg. But unless the enemy is throwing a P4 at your KV2, KV2 ain't that great at AT.
KV2 at AT is some sort of support. It won't do the job on it's own, but it will scare off if there is a zis nearby. IS-2 on the other hand is more agile and can "solo" enemies easier. Don't neglect the IS-2's [much] higher penetration values, especially in team games where Panther/Tiger/KT spam is a thing. Having SU85, KV2 and what not on the field leaves you wide open to Panther dives. That is, if the enemy is not 90% of COH2 players and actually uses the margins and flanks to flank and go behind you.
I have used KV-2 in team games and it does the job at scaring enemies. When a diving panther gets 240 dmg on the side you can see how fast the germans click "U". Also It does half of it's damage when not penetrating, so you always get a hit. And actually KV-2 does great while 1v1 fighting a panther, even form the front. When i preformed tests, to my suprise, KV-2 would sometimes win with much more health left than the IS would.