I live in alexandria VA. Like alexander said the food in that area outside of D.C. is fantastic.
Make sure you check out the grand canyon. That is definitely a must see on your trip through the west.
Something to consider is a guide book to #1 top destinations in each state. Might make it easier to know what to check out when driving through each state.
I would add to look at top destinations in states bordering the ones where you already know you will be traveling to see if there is something worth the detour.
Also, bring lots of media. The US is big. REALLY big. I the northeast you can drive through some of the states in 2-3 hours, but as you go farther west the distances between states and especially cities can stretch to hours and hours even on the Interstate highway system (which is the most boring way to travel).