"The RTS and Strategy genre is pretty much dead and unprofitable"
Then he proceeds to list very popular and profitable RTS'es.... Rts isnt dead, there just aren't many good ones that are coming out these days. So it would seem that it is dead.
Would it be that competitive/PvP RTS are pretty much "dead" a better phrase ? Take a look at the titles released on the last 5-10 years and now compare it to some strategy games such as Total War, Civ, HoI, Stellaris.
SC2: commander mode is more popular that the sum of all PvP players.
Paradox games: all have 10K avg people and above peaking at 20K
Civ 6: 30K peaking at 50K
Total WH: 15K avg
The recent "They are billions" has around 11K avg and 22K peak players.
Now take a look at: Grey goo, Cossacks, Sudden strike, Steel Division, Halo Wars, Blitzkrieg, Planetary Annihilation, DoW 2/3, Wargames and whatever other title you might think of. CoH2, AoE 2 HD and SC are pretty much the only exponents of the genre with a more or less memorable remark on Men of War which retains it's really niche public.